ODR4

Across TCGA patient cohorts, ODR4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,356 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ODR4-associated genes across cancer lineages are TLR3, SMC3, and ACVR2A. Each is linked with ODR4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ODR4-to-partner and partner-to-ODR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ODR4 versus TLR3 in OV, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODR4→partner) and Y-score (partner→ODR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TLR3 →	+0.754	+0.201	.004	.002	3	4
UCEC	SMC3 →	-0.456	-0.307	.005	.004	3	4
PDAC	ACVR2A →	-0.518	-0.289	<.001	<.001	3	4
BRCA	ZNF639 →	-0.444	-0.352	.003	.001	3	4
BRCA	UFSP2 →	+0.400	+0.345	<.001	.002	3	3
BRCA	NUDT12 →	+0.684	+0.260	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,356 associations by consensus.

ODR4 vs TLR3 — OV

Explore this scatter interactively →