ODR4

Across TCGA patient cohorts, ODR4 mutation is significantly associated with the RNA expression of many other genes, with 1,022 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODR4-associated genes across cancer lineages are RNU6-1234P, TAF9, and RNA5SP414. Each is linked with ODR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODR4-to-partner and partner-to-ODR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1234P grouped by ODR4-low versus ODR4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODR4→partner) and Y-score (partner→ODR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1234P →	+0.298	+4.402	<.001	.002	3	2
UCEC	TAF9 →	+0.867	+3.480	<.001	.002	3	1
UCEC	RNA5SP414 →	+0.585	+2.892	<.001	<.001	3	1
UCEC	FCGBP →	-1.164	-3.443	.003	.005	3	1
UCEC	UHRF1 →	+0.843	+3.917	.002	<.001	3	1
UCEC	STMN1P1 →	+0.466	+2.845	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,022 associations by consensus.

RNU6-1234P by ODR4 expression — SKCM

Explore this box plot interactively →