Across TCGA patient cohorts, ODF4 mutation is significantly associated with the RNA expression of many other genes, with 369 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODF4-associated genes across cancer lineages are RNA5SP419, TRIM73, and FCER1A. Each is linked with ODF4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF4-to-partner and partner-to-ODF4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF4→partner) and Y-score (partner→ODF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.575	+2.398	.002	.007	3	2
UCEC	TRIM73 →	+0.141	+3.606	.001	.001	3	1
UCEC	FCER1A →	-0.861	-3.435	.006	.005	3	1
UCEC	LSM10 →	+0.476	+3.346	.001	.005	3	1
UCEC	ZSCAN22 →	+0.388	+3.329	.009	.005	3	1
UCEC	BRICD5 →	+0.709	+3.191	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 369 associations by consensus.

Exploration

ODF4 survival (RNA) · tumor vs normal (RNA) · all ODF4 data types