ODF3L2

Across TCGA patient cohorts, ODF3L2 mutation is significantly associated with the RNA expression of many other genes, with 1,033 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ODF3L2-associated genes across cancer lineages are DDX3P3, RNU6-1292P, and PIN1P1. Each is linked with ODF3L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF3L2-to-partner and partner-to-ODF3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDX3P3 grouped by ODF3L2-low versus ODF3L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3L2→partner) and Y-score (partner→ODF3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DDX3P3 →	+0.130	+2.602	<.001	.002	3	2
UCEC	RNU6-1292P →	+0.271	+3.716	<.001	.002	3	2
UCEC	PIN1P1 →	+0.118	+2.564	.001	.002	3	2
UCEC	FXNP1 →	+0.138	+2.957	<.001	.009	3	2
LUAD	ZNF734P →	+0.425	+4.157	<.001	.003	3	2
SKCM	ZACNP1 →	+0.097	+3.427	.004	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,033 associations by consensus.

DDX3P3 by ODF3L2 expression — UCEC

Explore this box plot interactively →