ODF3L2

Across TCGA cell cohorts, ODF3L2 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ODF3L2-associated genes across cancer lineages are TAS2R7, LCN9, and PRAMEF14. Each is linked with ODF3L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF3L2-to-partner and partner-to-ODF3L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAS2R7 grouped by ODF3L2-low versus ODF3L2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3L2→partner) and Y-score (partner→ODF3L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAS2R7 →	+0.024	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	LCN9 →	+0.020	+5.266	<.001	.001	3	1
LUNG_NSCLC_LUAD	PRAMEF14 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	LCE1F →	+0.102	+4.662	<.001	.005	3	1
LARGE_INTESTINE	SCGB3A2 →	+0.389	+4.095	<.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.295	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TAS2R7 by ODF3L2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →