ODF3B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ODF3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,574 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ODF3B-associated GO terms across cancer lineages are Negative regulation of response to biotic stimulus, Negative regulation of immune response, and Antigen processing and presentation of peptide antigen via MHC class I. Each is linked with ODF3B in more than 14 cancer types. Because this analysis shows association rather than direction, both ODF3B-to-partner and partner-to-ODF3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of response to biotic stimulus grouped by ODF3B-low versus ODF3B-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3B→partner) and Y-score (partner→ODF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCNegative regulation of response to biotic stimulus →+0.115+1.682<.001<.001315
UPPER_AERODIGESTIVE_TRACTNegative regulation of immune response →+0.074+1.844<.001<.001314
UPPER_AERODIGESTIVE_TRACTAntigen processing and presentation of peptide antigen via MHC class I →+0.223+1.984<.001.003314
KIDNEYDefense response to virus →+0.086+1.595.002.006214
UPPER_AERODIGESTIVE_TRACTNegative regulation of innate immune response →+0.140+2.290<.001<.001313
UPPER_AERODIGESTIVE_TRACTPositive regulation of inflammatory response →+0.103+1.800<.001.004312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,574 associations by consensus.

Negative regulation of response to biotic stimulus by ODF3B expression — LUNG_NSCLC_LUSC

Box plot of Negative regulation of response to biotic stimulus in ODF3B-low vs ODF3B-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration