ODF3B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ODF3B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ODF3B-associated genes across cancer lineages are TNP1 and TMCO5A. Each is linked with ODF3B in more than 1 cancer types. Because this analysis shows association rather than direction, both ODF3B-to-partner and partner-to-ODF3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TNP1 grouped by ODF3B-low versus ODF3B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODF3B→partner) and Y-score (partner→ODF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINETNP1 →+0.128+4.415<.001.00731
LARGE_INTESTINETMCO5A →+0.019+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TNP1 by ODF3B expression — LARGE_INTESTINE

Box plot of TNP1 in ODF3B-low vs ODF3B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration