Across TCGA pan-cancer cohorts, ODF2-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ODF2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ODF2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ODF2-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

KIRC, ACC, and MESO are the cancer types where ODF2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.530	0.699	<.001	78	view →
ACC	DFS	Median	All	0.425	0.735	<.001	57	view →
MESO	OS	Median	All	0.211	0.747	<.001	41	view →
LGG	DFS	Median	All	0.295	0.459	<.001	41	view →
CESC	DFS	Median	All	0.768	0.870	.003	30	view →
PAAD	DFS	Median	II,III,IV	0.585	0.338	.005	27	view →
UVM	OS	Median	All	0.780	1.000	.015	24	view →
UCS	DFS	Tertile	IV	0.932	0.459	.024	24	view →
COAD	DFS	Quartile	All	0.858	0.690	.017	12	view →
LUAD	DFS	Tertile	IV	0.107	0.829	.010	12	view →
READ	DFS	Median	All	0.760	0.920	.017	10	view →
LIHC	DFS	Quartile	II,III,IV	0.242	0.463	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration

Same gene, other analysis: ODF2-AS1 tumor-vs-normal RNA expression · all ODF2-AS1 data types