ODC1

Across TCGA pan-cancer cohorts, ODC1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ODC1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ODC1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated ODC1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

LUAD, GBM, and UCEC are the cancer types where ODC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.407	0.931	.011	10	view →
GBM	DFS	Median	All	0.321	0.742	.012	5	view →
UCEC	DFS	Median	All	0.983	0.853	.036	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ODC1–LUAD (OS)

Open the LUAD breakdown →