ODC1

Across TCGA patient cohorts, ODC1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,458 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ODC1-associated genes across cancer lineages are SAMHD1, DENND3, and TRIM16L. Each is linked with ODC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ODC1-to-partner and partner-to-ODC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ODC1 versus SAMHD1 in HNSC, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ODC1→partner) and Y-score (partner→ODC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	-1.413	-1.191	<.001	<.001	3	3
HNSC	DENND3 →	-0.921	-1.140	.004	.006	3	3
HNSC	TRIM16L →	+2.176	+1.303	.006	.003	3	3
HNSC	MYO1F →	-1.097	-1.198	<.001	<.001	3	3
HNSC	C1orf162 →	-0.998	-1.198	<.001	<.001	3	3
LSCC	UBA7 →	-1.226	-0.683	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,458 associations by consensus.

ODC1 vs SAMHD1 — HNSC

Explore this scatter interactively →