ODC1

Across TCGA cell cohorts, ODC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,154 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ODC1-associated GO terms across cancer lineages are Nucleolar large rRNA transcription by RNA polymerase I, DNA-templated transcription termination, and rRNA metabolic process. Each is linked with ODC1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ODC1-to-partner and partner-to-ODC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleolar large rRNA transcription by RNA polymerase I grouped by ODC1-low versus ODC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ODC1→partner) and Y-score (partner→ODC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.130	+0.929	<.001	.002	3	18
BONE	DNA-templated transcription termination →	+0.114	+0.908	<.001	.002	3	17
BONE	rRNA metabolic process →	+0.129	+1.201	<.001	.001	3	16
BONE	Ribosomal small subunit biogenesis →	+0.135	+0.989	<.001	.001	3	16
BONE	Ribosome biogenesis →	+0.132	+1.210	<.001	.001	3	15
PANCREAS	Endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.101	+1.443	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,154 associations by consensus.

Nucleolar large rRNA transcription by RNA polymerase I by ODC1 expression — BONE

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