ODAPH

Across TCGA pan-cancer cohorts, ODAPH Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ODAPH data layer compared with 23 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ODAPH Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ODAPH expression acts as an unfavorable survival marker.

LIHC and READ are the cancer types where ODAPH Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	II,III,IV	0.048	0.429	<.001	6	view →
READ	DFS	Median	III,IV	0.182	0.746	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

ODAPH–LIHC (DFS)

Open the LIHC breakdown →