OCRL

Across TCGA patient cohorts, OCRL protein abundance is significantly associated with the RNA expression of many other genes, with 11,212 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible OCRL-associated genes across cancer lineages are CETN2, BCLAF3, and MCTS1. Each is linked with OCRL in more than 5 cancer types. Because this analysis shows association rather than direction, both OCRL-to-partner and partner-to-OCRL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OCRL versus CETN2 in LUAD, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCRL→partner) and Y-score (partner→OCRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CETN2 →	+0.566	+0.282	<.001	<.001	3	6
UCEC	BCLAF3 →	+0.487	+0.252	.002	.001	3	6
HNSC	MCTS1 →	+0.398	+0.249	<.001	.001	3	6
HNSC	PGRMC1 →	+0.738	+0.416	<.001	<.001	3	5
BRCA	SMARCA1 →	+1.015	+0.358	.001	<.001	3	5
UCEC	UBE2A →	+0.496	+0.245	<.001	.008	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,212 associations by consensus.

OCRL vs CETN2 — LUAD

Explore this scatter interactively →