OCM2

Across TCGA patient cohorts, OCM2 mutation is significantly associated with the RNA expression of many other genes, with 166 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OCM2-associated genes across cancer lineages are RNA5SP410, HSPE1-MOB4, and LLPHP1. Each is linked with OCM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OCM2-to-partner and partner-to-OCM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP410 grouped by OCM2-low versus OCM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCM2→partner) and Y-score (partner→OCM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP410 →	+0.783	+3.374	<.001	<.001	3	2
UCEC	HSPE1-MOB4 →	+0.204	+4.021	.001	.001	3	1
UCEC	LLPHP1 →	+0.120	+3.329	<.001	.005	3	1
UCEC	GPR75-ASB3 →	+0.119	+3.341	<.001	.007	3	1
UCEC	MIR6075 →	+0.345	+3.053	.002	.003	3	1
UCEC	RNA5SP411 →	+1.522	+2.978	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 166 associations by consensus.

RNA5SP410 by OCM2 expression — UCEC

Explore this box plot interactively →