OCM2

Across TCGA patient cohorts, OCM2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OCM2-associated genes across cancer lineages are PCNA, Rab25, and MEK1. Each is linked with OCM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both OCM2-to-partner and partner-to-OCM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by OCM2-low versus OCM2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCM2→partner) and Y-score (partner→OCM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.324	+3.169	.006	.020	2	1
UCEC	Rab25 →	-0.548	-3.169	.002	.020	2	1
UCEC	MEK1 →	+0.529	+3.169	.008	.020	1	1
UCEC	TIGAR →	+0.230	+3.196	.005	.010	1	1
UCEC	Caspase-7-cleavedD198 →	+0.758	+3.169	.019	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PCNA by OCM2 expression — UCEC

Explore this box plot interactively →