Across TCGA patient cohorts, OCLN RNA expression is significantly associated with the protein abundance of many other proteins, with 12,683 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible OCLN-associated proteins across cancer lineages are PLS1, OCLN_S370, and BSPRY. Each is linked with OCLN in more than 6 cancer types. Because this analysis shows association rather than direction, both OCLN-to-partner and partner-to-OCLN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OCLN→partner) and Y-score (partner→OCLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PLS1 →	+0.732	+0.858	.004	.001	3	7
HNSC	OCLN_S370 →	+1.271	+1.369	<.001	<.001	3	7
BRCA	BSPRY →	+0.604	+0.823	<.001	<.001	3	7
HNSC	EPB41L5 →	+0.377	+1.216	<.001	<.001	3	7
PDAC	OCLN_S408 →	+0.643	+0.849	<.001	<.001	3	6
BRCA	PLEKHA7 →	+0.378	+0.757	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,683 associations by consensus.

Exploration

OCLN survival (RNA) · tumor vs normal (RNA) · all OCLN data types