Across TCGA cell cohorts, OCLN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,654 significant associations in total. CNS shows the largest number of these associations.

The most reproducible OCLN-associated GO terms across cancer lineages are Positive regulation of blood-brain barrier permeability, Cardiac muscle cell-cardiac muscle cell adhesion, and Golgi to vacuole transport. Each is linked with OCLN in more than 11 cancer types. Because this analysis shows association rather than direction, both OCLN-to-partner and partner-to-OCLN results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OCLN→partner) and Y-score (partner→OCLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of blood-brain barrier permeability →	+0.326	+1.732	<.001	<.001	3	12
CNS	Cardiac muscle cell-cardiac muscle cell adhesion →	+0.873	+1.048	<.001	.005	3	11
OVARY	Golgi to vacuole transport →	+0.091	+1.523	<.001	<.001	3	11
LARGE_INTESTINE	Establishment of endothelial intestinal barrier →	+0.161	+1.531	<.001	<.001	3	10
PANCREAS	Septin cytoskeleton organization →	+0.143	+1.943	<.001	<.001	3	10
STOMACH	Maintenance of blood-brain barrier →	+0.198	+2.567	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,654 associations by consensus.

Exploration

OCLN survival (RNA) · tumor vs normal (RNA) · all OCLN data types