OCIAD1

Across TCGA patient cohorts, OCIAD1 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OCIAD1-associated genes across cancer lineages are ERK2, 14-3-3_beta, and JNK_pT183_Y185. Each is linked with OCIAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OCIAD1-to-partner and partner-to-OCIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by OCIAD1-low versus OCIAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCIAD1→partner) and Y-score (partner→OCIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.229	+2.000	.008	.032	3	2
UCEC	14-3-3_beta →	-0.121	-3.143	.007	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.235	-2.687	.001	.006	3	1
UCEC	MEK1 →	+0.446	+3.169	.006	.019	3	1
UCEC	MSH6 →	-0.568	-3.449	<.001	.005	3	1
UCEC	Notch1 →	+0.198	+2.335	.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

ERK2 by OCIAD1 expression — UCEC

Explore this box plot interactively →