OCA2

Across TCGA patient cohorts, OCA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,366 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OCA2-associated proteins across cancer lineages are EPB41L1_S650, CRMP1, and TNRC6A_S943. Each is linked with OCA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both OCA2-to-partner and partner-to-OCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OCA2 versus EPB41L1_S650 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OCA2→partner) and Y-score (partner→OCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EPB41L1_S650 →	+1.294	+0.869	.004	.003	3	5
LSCC	CRMP1 →	+0.550	+1.117	.001	<.001	3	4
HNSC	TNRC6A_S943 →	-0.379	-0.888	.002	.009	3	4
BRCA	TRIM2 →	+0.553	+0.670	<.001	<.001	3	4
PDAC	NEO1 →	+0.302	+0.316	<.001	.005	3	4
LUAD	PLAU →	-0.627	-0.502	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,366 associations by consensus.

OCA2 vs EPB41L1_S650 — HNSC

Explore this scatter interactively →