OCA2

Across TCGA patient cohorts, OCA2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,647 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OCA2-associated genes across cancer lineages are ARHGAP19-SLIT1, SEZ6L, and EEF1A2. Each is linked with OCA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OCA2-to-partner and partner-to-OCA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OCA2 versus ARHGAP19-SLIT1 in GBM, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OCA2→partner) and Y-score (partner→OCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP19-SLIT1 →	+0.498	+0.664	.004	.008	3	3
GBM	SEZ6L →	+1.586	+0.840	<.001	<.001	3	2
GBM	EEF1A2 →	+1.425	+1.193	<.001	<.001	3	2
GBM	SEC14L5 →	+1.427	+1.315	<.001	<.001	3	2
GBM	STMN2 →	+2.329	+1.241	<.001	<.001	3	2
GBM	TMEM59L →	+0.722	+0.817	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,647 associations by consensus.

OCA2 vs ARHGAP19-SLIT1 — GBM

Explore this scatter interactively →