OBSL1

Across TCGA patient cohorts, OBSL1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,992 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OBSL1-associated genes across cancer lineages are INHA, SPEG, and SLC4A3. Each is linked with OBSL1 in more than 6 cancer types. Because this analysis shows association rather than direction, both OBSL1-to-partner and partner-to-OBSL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OBSL1 versus INHA in LUAD, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OBSL1→partner) and Y-score (partner→OBSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	INHA →	+0.921	+0.233	<.001	<.001	3	7
BRCA	SPEG →	+0.865	+0.299	<.001	.002	3	6
LSCC	SLC4A3 →	+1.055	+0.370	<.001	<.001	3	5
BRCA	EXTL1 →	+0.669	+0.189	<.001	.003	3	5
CCRCC	CCDC8 →	+1.933	+0.413	<.001	<.001	3	5
BRCA	PXDN →	+1.139	+0.286	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,992 associations by consensus.

OBSL1 vs INHA — LUAD

Explore this scatter interactively →