OBSL1

Across TCGA cell cohorts, OBSL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,193 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible OBSL1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Cytoplasmic translation. Each is linked with OBSL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both OBSL1-to-partner and partner-to-OBSL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by OBSL1-low versus OBSL1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OBSL1→partner) and Y-score (partner→OBSL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of myoblast fusion →	+0.137	+1.761	<.001	<.001	3	14
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.095	+0.622	<.001	.008	3	14
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.082	+1.384	.003	<.001	3	13
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.156	+3.531	.001	<.001	3	13
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.106	+1.384	<.001	<.001	3	12
LARGE_INTESTINE	Nucleoside triphosphate metabolic process →	+0.065	+2.024	<.001	.007	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,193 associations by consensus.

Regulation of myoblast fusion by OBSL1 expression — OVARY

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