OBSCN-AS1

Across TCGA pan-cancer cohorts, OBSCN-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated OBSCN-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher OBSCN-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OBSCN-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and UVM show a favorable association.

ACC, KIRP, and UCEC are the cancer types where OBSCN-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Median	All	0.769	0.968	<.001	111	view →
KIRP	DFS	Tertile	II,III,IV	0.127	0.789	<.001	87	view →
UCEC	DFS	Tertile	All	0.760	0.890	<.001	68	view →
ESCA	OS	Median	II,III,IV	0.644	0.377	.004	27	view →
COAD	DFS	Quartile	II,III,IV	0.646	0.827	<.001	26	view →
UVM	OS	Quartile	All	0.850	0.457	.020	21	view →
PRAD	DFS	Median	All	0.716	0.830	<.001	18	view →
KIRC	DFS	Quartile	III,IV	0.277	0.575	.017	11	view →
LUAD	DFS	Quartile	II,III,IV	0.634	0.828	.035	9	view →
THYM	OS	Median	All	0.918	1.000	.009	9	view →
STAD	OS	Median	IV	0.639	0.348	.020	9	view →
THCA	DFS	Median	All	0.959	0.908	.022	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

OBSCN-AS1–ACC (OS)

Open the ACC breakdown →