OBP2A

Across TCGA pan-cancer cohorts, OBP2A RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of OBP2A’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where OBP2A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types OBP2A is over-expressed in tumor.

HNSC, BLCA, and COAD are the cancer types where OBP2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OBP2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.401	<.001	12	view →
BLCA	All	III,IV	+0.167	<.001	10	view →
COAD	All	II,III,IV	+0.188	<.001	7	view →
KIRC	All	III,IV	+0.074	.001	6	view →
THCA	All	All	+0.361	.006	5	view →
LUSC	All	II,III,IV	+0.457	.011	4	view →
LIHC	All	All	+0.057	.003	3	view →
LUAD	All	All	+0.465	.003	2	view →
BRCA	All	All	+0.271	.040	2	view →
CHOL	All	All	+0.100	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

OBP2A–HNSC

Open the HNSC breakdown →