OBI1

Across TCGA cell cohorts, OBI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,594 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible OBI1-associated GO terms across cancer lineages are Ribosomal protein import into nucleus, Protein localization to kinetochore, and Protein localization to condensed chromosome. Each is linked with OBI1 in more than 18 cancer types. Because this analysis shows association rather than direction, both OBI1-to-partner and partner-to-OBI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal protein import into nucleus grouped by OBI1-low versus OBI1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OBI1→partner) and Y-score (partner→OBI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Ribosomal protein import into nucleus →	+0.162	+0.845	<.001	<.001	3	19
OESOPHAGUS	Protein localization to kinetochore →	+0.185	+0.983	.002	.002	3	17
OESOPHAGUS	Protein localization to condensed chromosome →	+0.190	+0.866	.001	.004	3	16
BONE	Sister chromatid biorientation →	+0.200	+1.315	<.001	<.001	3	15
PANCREAS	Attachment of mitotic spindle microtubules to kinetochore →	+0.120	+0.756	<.001	<.001	3	15
OESOPHAGUS	Metaphase chromosome alignment →	+0.133	+0.848	.006	.008	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,594 associations by consensus.

Ribosomal protein import into nucleus by OBI1 expression — BREAST

Explore this box plot interactively →