OAZ3

Across TCGA pan-cancer cohorts, OAZ3 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated OAZ3 data layer compared with 4 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher OAZ3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated OAZ3 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

OV, ACC, and KICH are the cancer types where OAZ3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.436	0.322	<.001	94	view →
ACC	DFS	Tertile	All	0.197	0.746	<.001	82	view →
KICH	OS	Median	All	0.634	1.000	<.001	76	view →
LIHC	OS	Median	All	0.412	0.594	<.001	43	view →
KIRP	DFS	Tertile	All	0.796	0.920	.005	41	view →
UCS	OS	Tertile	IV	0.263	0.898	.036	24	view →
SKCM	DFS	Quartile	All	0.686	0.832	.002	18	view →
HNSC	OS	Median	IV	0.749	0.539	.007	15	view →
LUSC	DFS	Quartile	II,III,IV	0.297	0.498	.009	13	view →
THYM	OS	Tertile	II,III,IV	0.636	1.000	.004	11	view →
UVM	DFS	Quartile	III,IV	0.242	1.000	.010	8	view →
ESCA	OS	Quartile	II,III,IV	0.697	0.454	.023	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

OAZ3–OV (DFS)

Open the OV breakdown →