OAZ2

Across TCGA pan-cancer cohorts, OAZ2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated OAZ2 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher OAZ2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated OAZ2 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BRCA show a favorable association.

COAD, KIRC, and ACC are the cancer types where OAZ2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.364	0.620	<.001	81	view →
KIRC	OS	Tertile	All	0.744	0.565	<.001	68	view →
ACC	DFS	Quartile	All	0.246	0.809	<.001	33	view →
BRCA	OS	Tertile	III,IV	0.923	0.763	.001	31	view →
DLBC	OS	Tertile	All	1.000	0.601	.016	31	view →
UVM	DFS	Tertile	II,III,IV	0.362	0.719	.009	27	view →
SKCM	DFS	Median	III,IV	0.175	0.323	.005	25	view →
KIRP	DFS	Median	IV	0.039	0.526	.027	24	view →
PAAD	OS	Quartile	All	0.770	0.455	.007	21	view →
UCEC	DFS	Tertile	III,IV	0.844	0.706	.009	20	view →
LIHC	OS	Median	II,III,IV	0.754	0.470	.005	18	view →
THCA	DFS	Median	All	0.903	0.780	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

OAZ2–COAD (DFS)

Open the COAD breakdown →