OAS2

Across TCGA patient cohorts, OAS2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,549 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible OAS2-associated genes across cancer lineages are ETV7, SAMHD1, and DDX58. Each is linked with OAS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both OAS2-to-partner and partner-to-OAS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OAS2 versus ETV7 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OAS2→partner) and Y-score (partner→OAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.231	+0.859	<.001	<.001	3	10
UCEC	SAMHD1 →	+0.979	+0.851	<.001	<.001	3	10
HNSC	DDX58 →	+1.377	+0.834	<.001	<.001	3	10
OV	SLC15A3 →	+0.836	+0.752	<.001	<.001	3	10
BRCA	OAS3 →	+1.470	+0.967	<.001	<.001	3	10
HNSC	IFIH1 →	+1.316	+0.911	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,549 associations by consensus.

OAS2 vs ETV7 — BRCA

Explore this scatter interactively →