OARD1

Across TCGA patient cohorts, OARD1 mutation is significantly associated with the RNA expression of many other genes, with 83 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OARD1-associated genes across cancer lineages are MIR98, TRBV11-3, and IGHV1OR21-1. Each is linked with OARD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OARD1-to-partner and partner-to-OARD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR98 grouped by OARD1-low versus OARD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OARD1→partner) and Y-score (partner→OARD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR98 →	+0.338	+3.216	<.001	.002	3	1
UCEC	TRBV11-3 →	+0.323	+2.657	.004	.005	3	1
UCEC	IGHV1OR21-1 →	+0.891	+2.800	<.001	.005	3	1
SKCM	RNA5SP483 →	+0.381	+4.188	.004	.009	3	1
SKCM	RN7SKP119 →	+0.147	+5.080	<.001	.004	3	1
SKCM	USP12P2 →	+0.059	+4.215	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

MIR98 by OARD1 expression — UCEC

Explore this box plot interactively →