Across TCGA patient cohorts, OAF protein abundance is significantly associated with the RNA expression of many other genes, with 10,521 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OAF-associated genes across cancer lineages are SERPINE1, OLFML2B, and TIMP1. Each is linked with OAF in more than 6 cancer types. Because this analysis shows association rather than direction, both OAF-to-partner and partner-to-OAF results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OAF→partner) and Y-score (partner→OAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SERPINE1 →	+1.930	+0.673	<.001	.001	3	7
COAD	OLFML2B →	+1.099	+0.523	<.001	<.001	3	7
GBM	TIMP1 →	+1.271	+0.727	<.001	<.001	3	6
OV	FLT1 →	+0.976	+0.907	<.001	<.001	3	6
OV	LRRC32 →	+0.969	+0.580	<.001	<.001	3	6
OV	ITGA5 →	+1.127	+0.514	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,521 associations by consensus.

Exploration

OAF survival (RNA) · tumor vs normal (RNA) · all OAF data types