Across TCGA cell cohorts, OAF RNA expression is significantly associated with the go_rna of many other GO terms, with 4,706 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OAF-associated GO terms across cancer lineages are Carbohydrate biosynthetic process, Mitochondrial tRNA pseudouridine synthesis, and Regulation of extracellular matrix disassembly. Each is linked with OAF in more than 10 cancer types. Because this analysis shows association rather than direction, both OAF-to-partner and partner-to-OAF results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OAF→partner) and Y-score (partner→OAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Carbohydrate biosynthetic process →	+0.083	+1.976	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial tRNA pseudouridine synthesis →	+0.108	+1.150	.006	.005	3	10
LUNG_SCLC	Regulation of extracellular matrix disassembly →	+0.120	+1.681	<.001	<.001	3	9
BREAST	Regulation of cell-substrate junction organization →	+0.073	+1.534	.002	<.001	3	9
BREAST	Positive regulation of T cell migration →	+0.119	+1.607	<.001	.001	3	9
LUNG_NSCLC_LUSC	Positive regulation of protein localization to membrane →	+0.098	+1.734	.005	.005	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,706 associations by consensus.

Exploration

OAF survival (RNA) · tumor vs normal (RNA) · all OAF data types