Across TCGA cell cohorts, NYX RNA expression is significantly associated with the go_rna of many other GO terms, with 595 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NYX-associated GO terms across cancer lineages are Gluconeogenesis, Monosaccharide biosynthetic process, and Synaptic vesicle lumen acidification. Each is linked with NYX in more than 3 cancer types. Because this analysis shows association rather than direction, both NYX-to-partner and partner-to-NYX results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NYX→partner) and Y-score (partner→NYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Gluconeogenesis →	+0.076	+0.029	<.001	<.001	3	4
SKIN	Monosaccharide biosynthetic process →	+0.076	+0.029	<.001	<.001	3	3
SKIN	Synaptic vesicle lumen acidification →	+0.085	+0.034	.002	.001	3	3
BLOOD_Lymphoma	Regulation of mitochondrial membrane permeability →	+0.058	+0.266	<.001	.002	3	3
OVARY	Actin filament polymerization →	-0.076	-0.522	<.001	.007	3	3
OVARY	Response to potassium ion →	-0.088	-0.569	.002	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 595 associations by consensus.

Exploration

NYX survival (RNA) · tumor vs normal (RNA) · all NYX data types