Across TCGA cell cohorts, NYX protein abundance is significantly associated with the RNA expression of many other genes, with 3,217 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NYX-associated genes across cancer lineages are PRDX3, TRUB1, and SFXN4. Each is linked with NYX in more than 9 cancer types. Because this analysis shows association rather than direction, both NYX-to-partner and partner-to-NYX results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYX→partner) and Y-score (partner→NYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PRDX3 →	+1.751	+1.363	<.001	.002	3	10
LUNG_NSCLC_LUAD	TRUB1 →	+0.431	+0.601	.001	.001	3	7
LUNG_NSCLC_LUAD	SFXN4 →	+0.568	+0.705	<.001	<.001	3	7
BLOOD_Leukemia	SLC25A17 →	-0.461	-0.762	.005	.001	3	7
LUNG_NSCLC_LUAD	CRYZ →	+0.933	+0.600	.004	.001	3	6
STOMACH	DUSP5 →	+3.314	+1.744	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,217 associations by consensus.

Exploration

NYX survival (RNA) · tumor vs normal (RNA) · all NYX data types