Across TCGA cell cohorts, NYX protein abundance is significantly associated with the go_rna of many other GO terms, with 1,721 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NYX-associated GO terms across cancer lineages are Amino sugar catabolic process, HRI-mediated signaling, and Cardiac conduction. Each is linked with NYX in more than 4 cancer types. Because this analysis shows association rather than direction, both NYX-to-partner and partner-to-NYX results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NYX→partner) and Y-score (partner→NYX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Amino sugar catabolic process →	+0.124	+1.349	.003	.006	3	4
LUNG_NSCLC_LUSC	HRI-mediated signaling →	-0.132	-1.100	.001	.004	3	4
URINARY_TRACT	Cardiac conduction →	-0.169	-0.958	.002	.001	3	4
OVARY	Inositol biosynthetic process →	+0.120	+0.605	.009	.001	3	4
UPPER_AERODIGESTIVE_TRACT	Anterograde dendritic transport of neurotransmitter receptor complex →	-0.149	-1.153	<.001	<.001	3	4
CNS	Blood coagulation →	-0.061	-0.831	.008	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,721 associations by consensus.

Exploration

NYX survival (RNA) · tumor vs normal (RNA) · all NYX data types