Across TCGA patient cohorts, NYNRIN protein abundance is significantly associated with the RNA expression of many other genes, with 3,168 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NYNRIN-associated genes across cancer lineages are EFS, FZD6, and ABITRAM. Each is linked with NYNRIN in more than 2 cancer types. Because this analysis shows association rather than direction, both NYNRIN-to-partner and partner-to-NYNRIN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYNRIN→partner) and Y-score (partner→NYNRIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EFS →	+1.158	+0.517	.006	.003	3	3
COAD	FZD6 →	+1.182	+0.829	<.001	.004	3	2
BRCA	ABITRAM →	-0.453	-0.402	.001	.002	3	2
GBM	SAA2 →	+1.857	+0.575	.004	.002	3	2
BRCA	INTS8 →	-0.521	-0.504	.003	.002	3	2
BRCA	SLC39A2 →	+0.992	+0.632	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,168 associations by consensus.

Exploration

NYNRIN survival (RNA) · tumor vs normal (RNA) · all NYNRIN data types