Across TCGA patient cohorts, NYNRIN mutation is significantly associated with the total protein of many other genes, with 55 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NYNRIN-associated genes across cancer lineages are eEF2, Caspase-7-cleavedD198, and ATM. Each is linked with NYNRIN in more than 4 cancer types. Because this analysis shows association rather than direction, both NYNRIN-to-partner and partner-to-NYNRIN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYNRIN→partner) and Y-score (partner→NYNRIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	eEF2 →	+0.306	+3.601	.002	.001	3	5
COAD	Caspase-7-cleavedD198 →	+1.265	+3.815	<.001	<.001	3	4
UCEC	ATM →	-0.563	-2.188	<.001	<.001	3	4
UCEC	4E-BP1 →	+0.304	+3.247	<.001	<.001	3	4
UCEC	GAPDH →	+0.362	+1.874	.012	.002	3	3
SKCM	ER-alpha →	-0.126	-1.773	.024	.022	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 55 associations by consensus.

Exploration

NYNRIN survival (RNA) · tumor vs normal (RNA) · all NYNRIN data types