Across TCGA cell cohorts, NYNRIN mutation is significantly associated with the RNA expression of many other genes, with 1,336 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NYNRIN-associated genes across cancer lineages are KRTAP7-1, PAX9, and OR5K1. Each is linked with NYNRIN in more than 2 cancer types. Because this analysis shows association rather than direction, both NYNRIN-to-partner and partner-to-NYNRIN results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYNRIN→partner) and Y-score (partner→NYNRIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP7-1 →	+0.031	+4.867	<.001	.009	3	3
LARGE_INTESTINE	PAX9 →	+0.562	+2.043	.004	.001	3	3
STOMACH	OR5K1 →	+0.021	+3.624	<.001	<.001	3	2
OVARY	ACVR1C →	+0.273	+3.392	.004	.002	3	2
OVARY	RBPJL →	+0.027	+2.510	.003	.001	3	2
LARGE_INTESTINE	RNF227 →	+0.738	+2.716	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,336 associations by consensus.

Exploration

NYNRIN survival (RNA) · tumor vs normal (RNA) · all NYNRIN data types