NYAP2

Across TCGA patient cohorts, NYAP2 mutation is significantly associated with the RNA expression of many other genes, with 5,210 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NYAP2-associated genes across cancer lineages are ATP5MC1, IFRD1, and COX5BP8. Each is linked with NYAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NYAP2-to-partner and partner-to-NYAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5MC1 grouped by NYAP2-low versus NYAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP2→partner) and Y-score (partner→NYAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATP5MC1 →	+0.316	+1.988	.001	<.001	3	4
UCEC	IFRD1 →	+0.481	+2.148	<.001	<.001	3	4
READ	COX5BP8 →	+0.136	+3.140	<.001	.008	3	4
UCEC	EMID1 →	-0.896	-1.705	<.001	.003	3	4
SKCM	DPH5 →	+0.385	+2.025	<.001	<.001	3	4
UCEC	C12orf65 →	+0.228	+1.130	.003	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,210 associations by consensus.

ATP5MC1 by NYAP2 expression — UCEC

Explore this box plot interactively →