NYAP2

Across TCGA patient cohorts, NYAP2 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NYAP2-associated genes across cancer lineages are PCNA, Annexin-1, and ASNS. Each is linked with NYAP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NYAP2-to-partner and partner-to-NYAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by NYAP2-low versus NYAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP2→partner) and Y-score (partner→NYAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.159	+1.765	.007	.011	3	3
UCEC	Annexin-1 →	+0.358	+1.736	.013	.001	3	3
UCEC	ASNS →	+0.310	+2.502	.001	.001	3	3
UCEC	CDK1 →	+0.116	+1.498	.005	.032	3	3
COAD	PKC-b-II_pS660 →	-0.360	-2.321	.004	.032	3	3
STAD	Caspase-7-cleavedD198 →	+1.136	+3.169	.001	.019	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

PCNA by NYAP2 expression — UCEC

Explore this box plot interactively →