NYAP2

Across TCGA cell cohorts, NYAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,287 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NYAP2-associated GO terms across cancer lineages are Negative regulation of protein catabolic process, Process utilizing autophagic mechanism, and Autophagy. Each is linked with NYAP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both NYAP2-to-partner and partner-to-NYAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein catabolic process grouped by NYAP2-low versus NYAP2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP2→partner) and Y-score (partner→NYAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Negative regulation of protein catabolic process →	+0.073	+0.800	<.001	.003	3	7
LUNG_NSCLC_LUAD	Process utilizing autophagic mechanism →	+0.038	+0.441	<.001	.003	3	7
LUNG_NSCLC_LUAD	Autophagy →	+0.038	+0.441	<.001	.003	3	7
OVARY	Protein targeting to ER →	+0.076	+0.584	<.001	.006	3	6
CNS	Regulation of miRNA-mediated gene silencing →	+0.062	+0.602	.004	.007	3	6
LUNG_NSCLC_LUAD	Intrinsic apoptotic signaling pathway →	+0.044	+0.396	<.001	.007	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,287 associations by consensus.

Negative regulation of protein catabolic process by NYAP2 expression — LIVER

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