NYAP2

Across TCGA cell cohorts, NYAP2 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NYAP2-associated genes across cancer lineages are TPRX1, LYZL1, and HEMGN. Each is linked with NYAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NYAP2-to-partner and partner-to-NYAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TPRX1 grouped by NYAP2-low versus NYAP2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP2→partner) and Y-score (partner→NYAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TPRX1 →	+0.061	+3.854	<.001	.006	3	2
SOFT_TISSUE	LYZL1 →	+0.075	+4.169	<.001	.002	3	1
SOFT_TISSUE	HEMGN →	+0.039	+3.791	<.001	.007	3	1
SOFT_TISSUE	FTMT →	+0.052	+4.392	<.001	.004	3	1
SOFT_TISSUE	TAS2R42 →	+0.036	+3.884	.005	.005	3	1
SOFT_TISSUE	PRPS1L1 →	+0.140	+3.777	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

TPRX1 by NYAP2 expression — SOFT_TISSUE

Explore this box plot interactively →