NYAP1

Across TCGA patient cohorts, NYAP1 mutation is significantly associated with the RNA expression of many other genes, with 3,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NYAP1-associated genes across cancer lineages are RNU6-854P, SZRD1, and GTSE1. Each is linked with NYAP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NYAP1-to-partner and partner-to-NYAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-854P grouped by NYAP1-low versus NYAP1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP1→partner) and Y-score (partner→NYAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-854P →	+0.398	+4.350	<.001	.002	3	3
SKCM	SZRD1 →	+0.369	+1.957	<.001	<.001	3	3
UCEC	GTSE1 →	+0.888	+2.386	<.001	.003	3	3
UCEC	E2F2 →	+0.692	+2.332	.002	.003	3	3
SKCM	TXLNA →	+0.369	+1.944	.001	<.001	3	3
SKCM	PPM1G →	+0.266	+2.179	.006	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,196 associations by consensus.

RNU6-854P by NYAP1 expression — LIHC

Explore this box plot interactively →