NYAP1

Across TCGA cell cohorts, NYAP1 mutation is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NYAP1-associated genes across cancer lineages are C12orf40, GK2, and CGB2. Each is linked with NYAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NYAP1-to-partner and partner-to-NYAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C12orf40 grouped by NYAP1-low versus NYAP1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NYAP1→partner) and Y-score (partner→NYAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	C12orf40 →	+0.049	+4.786	<.001	.001	3	2
PANCREAS	GK2 →	+0.063	+5.139	<.001	<.001	3	2
BLOOD_Leukemia	CGB2 →	+1.265	+4.234	<.001	.003	3	2
LARGE_INTESTINE	C2CD4C →	+0.477	+2.743	.001	.001	3	2
LARGE_INTESTINE	FAS →	+1.404	+3.321	<.001	.003	3	2
BLOOD_Lymphoma	KRTAP4-1 →	+0.151	+4.867	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

C12orf40 by NYAP1 expression — PANCREAS

Explore this box plot interactively →