NXT2

Across TCGA pan-cancer cohorts, NXT2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NXT2 data layer compared with 28 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher NXT2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NXT2 expression acts as an unfavorable survival marker.

THYM and LUSC are the cancer types where NXT2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Median	All	0.604	0.975	<.001	30	view →
LUSC	DFS	Median	All	0.136	0.758	.002	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NXT2–THYM (OS)

Open the THYM breakdown →