NXT2

Across TCGA patient cohorts, NXT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,213 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NXT2-associated proteins across cancer lineages are CUL4B, THOC6, and RFC2. Each is linked with NXT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NXT2-to-partner and partner-to-NXT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NXT2 versus CUL4B in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NXT2→partner) and Y-score (partner→NXT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CUL4B →	+0.215	+0.634	<.001	<.001	3	5
LSCC	THOC6 →	+0.181	+0.678	<.001	<.001	3	4
LSCC	RFC2 →	+0.386	+0.997	.001	<.001	3	4
HNSC	STAG2 →	+0.196	+0.682	.003	.001	3	4
UCEC	SORBS3 →	-0.487	-0.535	.008	.006	3	3
CCRCC	UBE2F →	-0.205	-0.249	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,213 associations by consensus.

NXT2 vs CUL4B — LSCC

Explore this scatter interactively →