NXT2

Across TCGA cell cohorts, NXT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,690 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NXT2-associated GO terms across cancer lineages are Immunoglobulin heavy chain V-D-J recombination, Regulation of DNA damage checkpoint, and Mitotic G2/M transition checkpoint. Each is linked with NXT2 in more than 13 cancer types. Because this analysis shows association rather than direction, both NXT2-to-partner and partner-to-NXT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin heavy chain V-D-J recombination grouped by NXT2-low versus NXT2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXT2→partner) and Y-score (partner→NXT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Immunoglobulin heavy chain V-D-J recombination →	+0.153	+0.874	.002	<.001	3	14
OVARY	Regulation of DNA damage checkpoint →	+0.100	+0.971	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.103	+0.811	<.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome condensation →	+0.225	+0.885	<.001	.003	3	10
OESOPHAGUS	Establishment of mitotic sister chromatid cohesion →	+0.164	+1.161	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of G2/M transition of mitotic cell cycle →	+0.086	+0.738	.002	.005	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,690 associations by consensus.

Immunoglobulin heavy chain V-D-J recombination by NXT2 expression — OESOPHAGUS

Explore this box plot interactively →