Across TCGA pan-cancer cohorts, NXT1P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NXT1P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NXT1P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NXT1P1 is over-expressed in tumor.

HNSC and LUAD are the cancer types where NXT1P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NXT1P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	II,III,IV	+0.086	.034	3	view →
LUAD	Female	All	+0.088	.018	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NXT1P1 RNA expression & survival · all NXT1P1 data types