NXT1

Across TCGA cell cohorts, NXT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,274 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NXT1-associated GO terms across cancer lineages are Mitotic DNA replication, Nuclear DNA replication, and Cell cycle DNA replication. Each is linked with NXT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both NXT1-to-partner and partner-to-NXT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic DNA replication grouped by NXT1-low versus NXT1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NXT1→partner) and Y-score (partner→NXT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Mitotic DNA replication →	+0.125	+0.728	<.001	.001	3	9
SOFT_TISSUE	Nuclear DNA replication →	+0.155	+0.812	<.001	<.001	3	9
BLOOD_Myeloma	Cell cycle DNA replication →	+0.112	+0.633	.005	.002	3	9
LUNG_NSCLC_LUAD	Poly(A)+ mRNA export from nucleus →	+0.103	+0.797	<.001	.001	3	9
SOFT_TISSUE	Regulation of meiotic cell cycle →	+0.100	+0.671	.004	<.001	3	9
BLOOD_Lymphoma	Regulation of DNA replication →	+0.056	+0.676	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,274 associations by consensus.

Mitotic DNA replication by NXT1 expression — BLOOD_Lymphoma

Explore this box plot interactively →