NXPH4

Across TCGA pan-cancer cohorts, NXPH4 mass-spec protein is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NXPH4 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher NXPH4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NXPH4 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

GBM and LUAD are the cancer types where NXPH4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Quartile	All	0.157	0.614	.029	2	view →
LUAD	DFS	Median	All	0.871	0.301	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

NXPH4–GBM (DFS)

Open the GBM breakdown →