NXPH4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NXPH4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,617 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NXPH4-associated genes across cancer lineages are GAPDH, TPI1, and ENO2. Each is linked with NXPH4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NXPH4-to-partner and partner-to-NXPH4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NXPH4 versus GAPDH in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NXPH4→partner) and Y-score (partner→NXPH4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMGAPDH →+0.797+0.806<.001.00132
LSCCTPI1 →+0.838+1.051<.001<.00132
LSCCENO2 →+0.986+0.900.001<.00132
LUADSERPINI2 →-1.941-2.062.001.00332
GBMC3orf14 →+0.912+0.505.002.00332
GBMSUSD3 →-0.900-0.854<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,617 associations by consensus.

NXPH4 vs GAPDH — GBM

Per-sample scatter of NXPH4 vs GAPDH in GBM (Pearson r = 0.58).

Explore this scatter interactively →

Exploration